The University of Coimbra (UC; Portuguese: Universidade de Coimbra, pronounced [univɨɾsiˈðad(ɨ) dɨ kuˈĩbɾɐ]) is a Portuguese public university in Coimbra, Portugal. First established in Lisbon in 1290, it went through a number of relocations until moving permanently to Coimbra in 1537. The university is among the oldest universities in continuous operation in the world, the oldest in Portugal, and played a influential role in the development of higher education in the Portuguese-speaking world. In 2013, UNESCO declared the university a World Heritage Site, noting its architecture, unique culture and traditions, and historical role.

The contemporary university is organized into eight faculties, granting bachelor's (licenciado), master's (mestre) and doctorate (doutor) degrees in nearly all major fields. It lends its name to the Coimbra Group of European research universities founded in 1985, of which it was a founding member. Enrolling over 20,000 students, about 10% of whom are international, it is one of Portugal's most cosmopolitan universities

Coimbra's alumni over the centuries include Portugal's national poet Luís de Camões, the mathematician Pedro Nunes, many statemen, prime ministers and presidents of Portugal, and Nobel Prize laureate António Egaz Moniz.