Monash also has a research and teaching center in Prato, Italy, a graduate research school in Mumbai, India, and a graduate school in Suzhou, China. Monash University courses are also delivered at other locations, including South Africa.

Monash is home to major research facilities, including the Monash Law School, the Australian Synchrotron, the Monash Science Technology Research and Innovation Precinct (STRIP), the Australian Stem Cell Centre, Victorian College of Pharmacy, and 100 research centers and 17 co-operative research centers. In 2016, its total revenue was over $2.2 billion (AUD), with an external research income of around $282 million. In 2016, Monash enrolled over 50,000 undergraduate and over 22,000 graduate students. It has more applicants than any other university in the state of Victoria.

Monash is a member of Australia's Group of Eight research universities, a member of the ASAIHL, and the only Australian member of the M8 Alliance of Academic Health Centers, Universities, and National Academies. Monash is one of the Australian universities to be ranked in the École des Mines de Paris (Mines ParisTech) ranking on the basis of the number of alumni listed among CEOs in the 500 largest worldwide companies. Monash is consistently ranked among the world's top 55-70 universities in the QS World University Rankings