The School of Information Sciences, also The iSchool at Illinois, is an undergraduate and graduate school at the University of Illinois at Urbana–Champaign. Its Master of Science in Library and Information Science is currently accredited in full good standing by the American Library Association. The school is a charter member of the iSchool initiative.

The school offers the Bachelor of Science in Information Sciences, the Master of Science in Library and Information Science (MS/LIS; comparable to the Master of Library and Information Science), Master of Science in Information Management (MS/IM), Master of Science in Bioinformatics, a Certificate of Advanced Study (CAS), and a PhD. Pathways available to BS/IS students include Information & Culture, Data & Society, Data Analytics/Science, and Human Computer Interaction (HCI)/User Experience (UX). Specializations available to MS/LIS students include Youth Services, K–12 School Librarianship, Special Collections, Community Informatics, Socio-technical Data Analytics, and Data Curation. The School's PhD program in LIS, the oldest such program in the country, is primarily oriented towards interdisciplinary research.

Students seeking the MS/LIS, MS/IM, or CAS degree can earn their degree as an on-campus student or as a distance student via the Leep online learning option. For doctoral students, at least one year of residency is required on campus.