The Pratt School of Engineering is located at Duke University in the United States. The school's associated research, education, alumni and service-to-society efforts are collectively known as Duke Engineering.

Research expenditures at Duke Engineering exceed $88 million per year. Its faculty is highly ranked in overall research productivity among U.S. engineering schools by Academic Analytics. Ten members of the Duke Engineering faculty are members of the prestigious National Academy of Engineering.

The Pratt School of Engineering also maintains these academic departments:

• Biomedical Engineering
• Civil & Environmental Engineering
• Electrical & Computer Engineering
• Thomas Lord Department of Mechanical Engineering & Materials Science

Duke engineering faculty and alumni have contributed to a number of important high-impact technologies, including clinical ultrasound imaging, restoration of hearing by cochlear implant, mega-pixel photography and metamaterials.

The school was created by Duke's Board of Trustees in 1939. It was named in 1999 following a $35 million gift by Edmund T. Pratt Jr., a 1947 graduate and former chief executive of Pfizer. The Duke University Pratt School of Engineering celebrated its 75th anniversary in 2014–2015.

Duke Engineering is led by Vinik Dean of Engineering Ravi V. Bellamkonda.