The Wharton School of the University of Pennsylvania (/ˈhwɔːrtən/ WHAWR-tən; also known as Wharton Business School, the Wharton School or simply Wharton) is the business school of the University of Pennsylvania, a private Ivy League university in Philadelphia. Established in 1881 through a donation from Joseph Wharton, the Wharton School is the world's oldest collegiate school of business.

The Wharton School awards Bachelor of Science in Economics degrees at the undergraduate level and Master of Business Administration degrees at the postgraduate level, both of which require the selection of a major. Wharton also offers a doctoral program and houses, or co-sponsors, several diploma programs either alone or in conjunction with the other schools at the university.

Wharton's MBA program is ranked No. 5 in the United States according to Forbes and No. 1 in the United States according to the 2020 U.S. News & World Report ranking. Meanwhile, Wharton's MBA for Executives and undergraduate programs are ranked No. 3 and No. 1 in the United States respectively by U.S. News. MBA graduates of Wharton earn an average $159,815 first year base pay not including bonuses, the highest of all the leading schools. Wharton's MBA program is tied for the highest in the United States with an average GMAT score of 732 (97th percentile) for its entering class.

Wharton school alumni include former U.S. President Donald Trump, SpaceX founder Elon Musk, and billionaire investor Warren Buffett. Current and former CEOs of Fortune 500 companies including Alphabet Inc., General Electric, Boeing, Pfizer, Comcast, Oracle, PepsiCo and Johnson & Johnson are also Wharton School alumni.